Predicting Protein Conformational States with AI (2026)
How AI is moving beyond static AlphaFold structures to predict protein conformational states and ensembles in 2026, the methods, the limits, and why it matters.
RFdiffusion 2: How AI Now Designs Functional Proteins (2026)
RFdiffusion 2 explained — what changed, how it pairs with ProteinMPNN, success rates on real binder campaigns, and the open problems.
AlphaFold 3 Architecture: How Diffusion Predicts Biomolecular Structure (2026)
AlphaFold 3 architecture explained: the Pairformer, the diffusion module, how it predicts proteins, DNA, RNA, ligands and complexes, and its accuracy and limits in 2026.